SeWeR is an acronym, stands for SEquence analysis using WEb Resources. In addition to its common *dirty* use, the word SeWeR also has two meanings- first, "a medieval servant or household officer of high rank in charge of serving dishes at the table and sometimes of seating and tasting" and the second one, "one who sews". SeWeR fits all of these definitions. First, it is *dirty* at the code level. Second, it serves. It serves you a single door to all the common web-based services for sequence analysis. And it sews. It sews all these services together. For a refined mind, SeWeR is an integrated portal to common web-based services in bioinformatics.