Align-m is an accurate and highly versatile multiple alignment program. It consists of 3 modules, S2P, P2P and P2M (see figure, manual), which can be used separately or consecutively to accomplish several tasks:
- Multiple sequence alignment
- Include extra information to guide the sequence alignment
- Multiple structure alignment
- Homology modeling by (iteratively) combining sequence and structure alignment data
- 'Filtering' of Blast or other pairwise alignments
- Combining many alignments into 1 consensus
- Multiple genome alignment (can cope with rearrangements)
Download the windows x86 version. You may require the Borland cc3250.dll for this, to be placed somewhere in your path (e.g. c:\windows\system32).