VHMPT is a graphical Viewer and editor for Helical Membrane Protein Topologies. It is a program that can automatically generate a schematic 2D topology for a protein with transmembrane helices; the input requires only the protein's amino acid sequence and sequence range of its helices. Through an interactive graphical interface, VHMPT allows users to modify layout of the generated topology, as well as annotate with arrows and texts. In addition, with a multiple-sequence alignment, VHMPT can color-code the degree of conservation for each of the aligned amino acids, thus highly conserved (or variable) amino acids or topology regions of the interested protein can be readily recognized and visualized in contrasting colors.
